Nimesulide - Actions and Uses Kim D Rainsford

ISBN: 9781280413148

Published: January 1st 2005

ebook

444 pages


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Nimesulide - Actions and Uses  by  Kim D Rainsford

Nimesulide - Actions and Uses by Kim D Rainsford
January 1st 2005 | ebook | PDF, EPUB, FB2, DjVu, talking book, mp3, RTF | 444 pages | ISBN: 9781280413148 | 6.23 Mb

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leadingMoreNimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation.

It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs. The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.



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